Pleurotus ostreatus is a subject of growing interest in integrative oncology research due to its specific proteins, lectins (POL). This page explores how these bioactive molecules intervene in cell cycle regulation by inhibiting the proliferation of certain oncological lines. The studies presented here highlight the mechanisms through which these fungal lectins promote apoptosis (programmed cell death) and support the body’s natural defenses. In an integrative health approach, the Oyster mushroom thus emerges as a promising biological resource for supporting cellular research and the development of future complementary care strategies.

Structure and properties of the oyster mushroom (Pleurotus ostreatus) lectin  – Massimiliano Perduca & Al.
Experiment: Molecular characterization
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Summary: This study reports the 3D structure and binding properties of the Oyster Mushroom Lectin (POL), a protein purified from the fruiting body of Pleurotus ostreatus. Researchers highlighted in vitro antiproliferative effects on human oncological cell lines. The structure of this protein shows a specific ability to bind to carbohydrates, confirming its biological interest. Due to these properties, the oyster mushroom lectin appears as a promising subject for integrative oncology research and the development of future supportive protocols.

Mushroom Lectins as Promising Anticancer Substances – Ram Sarup Singh & Al.
Experiment: Review
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Summary: This comprehensive scientific review analyzes the role of lectins—carbohydrate-binding proteins—found in various mushroom species. The authors highlighted the antiproliferative properties of these molecules, which are capable of influencing cell growth regulation. The study also emphasizes the ability of fungal lectins to induce apoptosis (programmed cell death) in certain oncological cell models. These findings position fungal lectins as promising natural compounds for research and the development of new supportive strategies in oncology.